Searchable abstracts of presentations at key conferences in endocrinology

ea0029p647 | Diabetes | ICEECE2012

Urinary pentosidine concentration in patients with type 2 diabetes and risk of vascular complications

Tanaka M , Takeda S , Kawai T , Meguro S , Irie J , Saisho Y , Itoh H

Aims: We investigated the association between urinary pentosidine concentration (UPC) and vascular complications.Methods: UPC was measured in 66 patients (31 men and 35 women) with type 2 diabetes. We compared UPC between patients with and without diabetic microangiopathy, and between patients with and without macroangiopathy (cerebral infarction (CI), coronary artery disease, and peripheral arterial disease). Stepwise regression analysis was performed t...

ea0029oc5.4 | Obesity Basic | ICEECE2012

Bile acid binding resin shows anti-obese effect through the modifications of intestinal microbiota

Kusumoto Y. , Irie J. , Tagawa H. , Itoh A. , Kato M. , Kobayashi N. , Tanaka K. , Yamada S. , Kawai T. , Itoh H.

The growing epidemic of obesity has led health professionals to understand the pathophysiology of obesity and its complications. Gut microbiota are of special interest, since some kinds of microbiota such as Bacteroides are less in obese persons and some microbiota induce obesity in animals by effective fat storage through microbiota-mediated intestinal Fiaf (Fasting-induced adipose factor) suppressions. Recently, bile acid-binding resins (BARs), non-absorbable drug for dyslip...